INTRODUCTION TO BIOCHEMISTRY
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(A) Aspirin (B) Allopurinol
(C) Colchicine (D) Probenecid
Ans: B
2. Which of the following is required for the crystallization and storage of the hormone insulin?
(A) Mn++ (B) Mg++
(C) Ca++ (D) Zn++
Ans: D
3. Oxidation of which substance in the body yields the most calories
(A) Glucose (B) Glycogen
(C) Protein (D) Lipids
Ans: D
4. Milk is deficient in which vitamins?
(A) Vitamin C (B) Vitamin A
(C) Vitamin B2 (D) Vitamin K
Ans: A
5. Milk is deficient in which mineral?
(A) Phosphorus (B) Sodium
(C) Iron (D) Potassium
Ans: C
6. Synthesis of prostaglandins is inhibited by
(A) Aspirin (B) Arsenic
(C) Fluoride (D) Cyanide
Ans: A
7. HDL is synthesized and secreted from
(A) Pancreas (B) Liver
(C) Kidney (D) Muscle
Ans: B
8. Which are the cholesterol esters that enter cells through the receptor-mediated endocytosis of lipoproteins hydrolyzed?
(A) Endoplasmin reticulum
(B) Lysosomes
(C) Plasma membrane receptor
(D) Mitochondria
Ans: B
9. Which of the following phospholipids is localized to a greater extent in the outer leaflet of the membrane lipid bilayer?
(A) Choline phosphoglycerides
(B) Ethanolamine phosphoglycerides
(C) Inositol phosphoglycerides
(D) Serine phosphoglycerides
Ans: A
10. All the following processes occur rapidly in the membrane lipid bilayer except
(A) Flexing of fatty acyl chains
(B) Lateral diffusion of phospholipids
(C) Transbilayer diffusion of phospholipids
(D) Rotation of phospholipids around their long axes
Ans: C
11. Which of the following statement is correct about membrane cholesterol?
(A) The hydroxyl group is located near the centre of the lipid layer
(B) Most of the cholesterol is in the form of a cholesterol ester
(C) The steroid nucleus form forms a rigid, planar structure
(D) The hydrocarbon chain of cholesterol projects into the extracellular fluid
Ans: C
12. Which one is the heaviest particulate
component of the cell?
(A) Nucleus
(B) Mitochondria
(C) Cytoplasm
(D) Golgi apparatus
Ans: A
13. Which one is the largest particulate of the cytoplasm?
(A) Lysosomes
(B) Mitochondria
(C) Golgi apparatus
(D) Endoplasmic reticulum
Ans: B
14. The degradative processes are categorized under the heading of
(A) Anabolism
(B) Catabolism
(C) Metabolism
(D) None of the above
Ans: B
15. The exchange of material takes place
(A) Only by diffusion
(B) Only by active transport
(C) Only by pinocytosis
(D) All of these
Ans: D
16. The average pH of Urine is
(A) 7.0 (B) 6.0
(C) 8.0 (D) 0.0
Ans: B
17. The pH of blood is 7.4 when the ratio between H2CO3 and NaHCO3 is
(A) 1: 10 (B) 1: 20
(C) 1: 25 (C) 1: 30
Ans: B
18. The phenomenon of osmosis is opposite to that of
(A) Diffusion
(B) Effusion
(C) Affusion
(D) Coagulation
Ans: A
19. The surface tension in the intestinal lumen between fat droplets and aqueous medium is decreased by:
(A) Bile Salts (B) Bile acids
(C) Conc. H2SO4 (D) Acetic acid
Ans: A
20. Which of the following is located in the mitochondria?
(A) Cytochrome oxidase
(B) Succinate dehydrogenase
(C) Dihydrolipoyl dehydrogenase
(C) All of these
Ans: D
21. The most active site of protein synthesis is the
(A) Nucleus (B) Ribosome
(C) Mitochondrion (D) Cell sap
Ans: B
22. The fatty acids can be transported into and out of mitochondria through
(A) Active transport
(B) Facilitated transfer
(C) Non-facilitated transfer
(D) None of these
Ans: B
23. Mitochondrial DNA is
(A) Circular double stranded
(B) Circular single-stranded
(C) Linear double helix
(D) None of these
Ans: A
24. The absorption of intact protein from the gut in the foetal and newborn animals takes place by
(A) Pinocytosis
(B) Passive diffusion
(C) Simple diffusion
(D) Active transport
Ans: A
25. The cellular organelles called “suicide bags” are
(A) Lysosomes
(B) Ribosomes
(C) Nucleolus
(D) Golgi’s bodies
Ans: A
26. From the biological viewpoint, solutions can be grouped into
(A) Isotonic solution
(B) Hypotonic solutions
(C) Hypertonic solution
(D) All of these
Ans: D
27. Bulk transport across the cell membrane is accomplished by
(A) Phagocytosis
(B) Pinocytosis
(C) Extrusion
(D) All of these
Ans: D
28. The ability of the cell membrane to act as a selective barrier depends upon
(A) The lipid composition of the membrane
(B) The pores which allow small molecules
(C) The special mediated transport systems
(D) All of these
Ans: D
29. Carrier protein can:
(A) Transport only one substance
(B) Transport more than one substance
(C) Exchange one substance for another
(D) Perform all of these functions
Ans: D
30. A lipid bilayer is permeable to
(A) Urea
(B) Fructose
(C) Glucose
(D) Potassium
Ans: A
31. The Golgi complex
(A) Synthesizes proteins
(B) Produces ATP
(C) Provides a pathway for transporting chemicals
(D) Forms glycoproteins
Ans: D
32. The following points about microfilaments are true except
(A) They form cytoskeleton with microtubules
(B) They provide support and shape
(C) They form intracellular conducting channels
(D) They are involved in muscle cell contraction
Ans: C
33. The following substances are cell inclusions except
(A) Melanin
(B) Glycogen
(C) Lipids
(D) Centrosome
Ans: D
34. Fatty acids can be transported into and out of cell membranes by
(A) Active transport
(B) Facilitated transport
(C) Diffusion
(D) Osmosis
Ans: B
35. Enzymes catalyzing electron transport are present mainly in the
(A) Ribosomes
(B) Endoplasmic reticulum
(C) Lysosomes
(D) Inner mitochondrial membrane
Ans: D
36. Mature erythrocytes do not contain
(A) Glycolytic enzymes
(B) HMP shunt enzymes
(C) Pyridine nucleotide
(D) ATP
Ans: C
37. In mammalian cells rRNA is produced mainly in the
(A) Endoplasmic reticulum
(B) Ribosome
(C) Nucleolus
(D) Nucleus
Ans: C
38. Genetic information of nuclear DNA is transmitted to the site of protein synthesis by
(A) rRNA
(B) mRNA
(C) tRNA
(D) Polysomes
Ans: D
39. The powerhouse of the cell is
(A) Nucleus
(B) Cell membrane
(C) Mitochondria
(D) Lysosomes
Ans: C
40. The digestive enzymes of cellular compounds are confined to
(A) Lysosomes
(B) Ribosomes
(C) Peroxisomes
(D) Polysomes
Ans: A